{"id":184,"date":"2023-08-24T13:46:38","date_gmt":"2023-08-24T13:46:38","guid":{"rendered":"https:\/\/geographicatrophy.uk\/?page_id=184"},"modified":"2024-03-14T10:10:43","modified_gmt":"2024-03-14T10:10:43","slug":"unmet-need-in-ga","status":"publish","type":"page","link":"https:\/\/geographicatrophy.uk\/unmet-need-in-ga\/","title":{"rendered":"Unmet need in GA"},"content":{"rendered":"
\n\n\n\n
\n\t
\n\t\t
\n\t\t\t
\n\t\t\t\t
\n \t\t\t\t\t\t\t\t\t\t\t

The unmet need in
geographic atrophy<\/h1>\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\t\t\t\t\t\"Geographic\n\t\t\t
<\/div>\n\t\t\n\t<\/div>\n<\/div>\n\n\t<\/div>\n\n
\n
\n
<\/div>\n<\/div>\n\n
\n
\n
\n

Patients & caregivers<\/h2>\n<\/div>\n\n
\n

Geographic atrophy has a notable disease burden for patients and for those who care for them. The loss of vision can be traumatic and impacts many aspects of a patient\u2019s financial and social life, including relationships, hobbies and daily activities.1<\/sup><\/p>\n<\/div><\/div>\n\n\n\n

\n
\"\"<\/figure><\/div>\n\n
\n
<\/div>\n<\/div><\/div>\n\n\n\n
\n

Patients & caregivers<\/h2>\n<\/div>\n\n
\n

Geographic atrophy has a notable disease burden for patients and for those who care for them. The loss of vision can be traumatic and impacts many aspects of a patient\u2019s financial and social life, including relationships, hobbies and daily activities.1<\/sup><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n

\n
<\/div>\n<\/div>\n\n
\n
\n
<\/div>\n<\/div>\n\n
\n
\n
\n
\"\"<\/figure>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n

Geographic atrophy is a leading cause of legal blindness<\/strong> and is estimated to account for around 25%<\/strong> of all cases attributed to AMD.2<\/sup><\/p>\n<\/div><\/div>\n\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n

Prevalence of late AMD is expected to increase further<\/strong> with the aging population, and it is predicted there will be over 18 million cases<\/strong> by 2040.3<\/sup><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n

\n
\n

Devastating emotional and financial impact on both patients and their caregivers, and a substantial negative impact on an individual\u2019s ability to perform essential and enjoyable daily activities.1,4\u20136<\/sup><\/p>\n<\/div>\n\n

\n
\n
\n
\n
\n
\"\"<\/figure><\/div><\/div>\n\n\n\n
\n

Driving<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

\n
\n
\n
\"\"<\/figure><\/div><\/div>\n\n\n\n
\n

Reading<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

\n
\n
\n
\"\"<\/figure><\/div><\/div>\n\n\n\n
\n

Travelling<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

\n
\n
\n
\"\"<\/figure><\/div><\/div>\n\n\n\n
\n

Hobbies<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

\n
\n
\n
\"\"<\/figure><\/div><\/div>\n\n\n\n
\n

Working<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div><\/div>\n<\/div><\/div>\n\n

\n
<\/div>\n<\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n
\n
\n
<\/div>\n<\/div>\n\n
\n
\n

A new survey of those living with geographic atrophy reveals that this disease comes with a large emotional burden and loss of independence.6<\/sup><\/h2>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n\n

The global Geographic Atrophy Insights Survey (GAINS) (N=203), conducted by The Harris Poll and sponsored by Apellis Pharmaceuticals, found that for nearly 7 in 10 (68%) of people living with GA, the impact of vision decline on their independence and quality of life is worse than they expected.6<\/sup><\/p>\n<\/div>\n<\/div><\/div>\n\n

\n
<\/div>\n<\/div>\n\n
\n
\n
\n
\"\"<\/figure>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n

(35<\/sub>%) withdrew<\/strong> from their social lives<\/strong> due to vision loss6<\/sup><\/p>\n<\/div><\/div>\n\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n

agree the impact<\/strong> of vision decline on quality of life (QoL) <\/strong>and independence<\/strong> is worse than they expected<\/strong>6<\/strong><\/sup><\/p>\n<\/div><\/div>\n\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n

(77<\/sub>%) agree their vision was impacted faster than they expected<\/strong>6<\/strong><\/sup><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n

\n
\n
\n
\"\"<\/figure>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n

of those who have difficulty recognising faces feel frustrated<\/strong> when they cannot recognise the faces of friends or family<\/strong>6<\/strong><\/sup><\/p>\n<\/div><\/div>\n\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n

of people living with GA agree that prior to their diagnosis, they attributed their vision loss<\/strong> to a natural part of ageing<\/strong>6<\/strong><\/sup><\/p>\n<\/div><\/div>\n\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n

wish they had understood the irreversible impact geographic atrophy would have on their vision<\/strong>6<\/strong><\/sup><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n

\n
<\/div>\n<\/div>\n\n
\n
\n

Living with geographic atrophy can take a deep emotional toll. Of those who have difficulty recognising faces due to vision loss (n=61), 49% feel frustrated<\/strong> when they cannot recognise the faces of friends or family. Furthermore, out of all respondents, ~1 in 3 (35%) withdrew from their social lives because of geographic atrophy. These hardships also often come as a surprise, as most (77%) people living with Geographic Atrophy agree that the impact on vision is happening faster than they anticipated<\/strong>.6<\/strong><\/sup><\/p>\n<\/div>\n\n

\n
<\/div>\n<\/div>\n\n
\n

People living with GA report feeling:<\/strong>6<\/strong><\/sup><\/p>\n<\/div><\/div>\n<\/div><\/div>\n\n

\n
\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n
\"\"<\/figure>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n
\n

Despite these challenges, those living with geographic atrophy wish there were more educational materials for patients and caregivers (86%). There is a meaningful opportunity to empower them by providing more support as they navigate a future living with geographic atrophy.6<\/sup><\/p>\n<\/div>\n\n

\n
<\/div>\n<\/div><\/div>\n<\/div><\/div>\n\n
\n
\n
\n
\"\"<\/figure>\n<\/div>\n\n
\n

<\/p>\n<\/div>\n\n

\n

<\/p>\n<\/div>\n\n

\n

want more information and options<\/strong> about geographic atrophy to feel empowered to take control of their disease6<\/sup><\/p>\n<\/div><\/div>\n\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n
\n

<\/p>\n<\/div>\n\n

\n

<\/p>\n<\/div>\n\n

\n

wish there were more educational materials<\/strong> available for patients and caregivers6<\/sup><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n

\n
<\/div>\n<\/div><\/div>\n<\/div><\/div>\n\n
\n
<\/span>\"\"
\n
<\/div>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n
\n
\n
\"\"<\/figure>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n

What is geographic atrophy<\/h2>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n
\n
Find out more about GA<\/a><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n
\n
<\/div>\n<\/div>\n\n
\n
<\/div>\n<\/div>\n\n
\n
<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n
\n
<\/div>\n<\/div><\/div><\/div>\n<\/div>\n\n\n
\n
\n
\n